A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/44 (2006.01) A61P 31/10 (2006.01)
Patent
CA 2733553
A topical composition for treating nail fungal infections that utilizes an acidic antifungal agent with a molecular weight no greater than 170 Daltons in a formulation having a pH less than or equal to the pKa of the acidic antifungal agent plus one. Possible antifungal agents include omadine, octanoic acid, sorbic acid, hexanoic acid, and benzoic acid. The antifungal agent can be combined with a delivery system such as a lacquer, a gel, a patch, or a hydrating system. A second therapeutic agent such as a 5-fluorocystine or terbinafme can be included.
L'invention concerne une composition topique pour traiter des infections fongiques de l'ongle qui utilisent un agent antifongique acide ayant un poids moléculaire qui nest pas supérieur à 170 Daltons dans une formulation ayant un pH inférieur ou égal au pKa de l'agent antifongique acide, plus un. Des agents antifongiques possibles comprennent de l'omadine, de l'acide octanoïque, de l'acide sorbique, de l'acide hexanoïque, et de l'acide benzoïque. L'agent antifongique peut être combiné avec un système de délivrance comme une laque, un gel, une pastille, ou un système hydratant. Un second agent thérapeutique, comme de la 5-fluorocystine ou de la terbinafine, peut être inclus.
Cohen David M.
Cooper Eugene R.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Dermworx Incorporated
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