Local delivery of medications to the heart

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/00 (2006.01) A01N 25/34 (2006.01) A61B 5/055 (2006.01) A61B 8/00 (2006.01) A61F 2/00 (2006.01) A61K 9/16 (2006.01) A61K 9/48 (2006.01) A61K 41/00 (2006.01) A61K 49/00 (2006.01)

Patent

CA 2342912

Microparticle compositions are provided containing pharmacological agents effective when locally released at the heart. They are introduced into the bloodstream and their location is monitored by ultrasound or other means. The microparticles are ruptured with ultrasound energy at a predetermined ultrasound condition when such energy is directed locally at the region of the heart.

L'invention concerne des compositions de microparticules, contenant des agents pharmacologiques efficaces lorsqu'on les libère localement au niveau du coeur. Ces agents sont introduits dans la circulation sanguine et leur emplacement est surveillé par des ultrasons ou d'autres moyens. Les microparticules sont brisées par l'énergie ultrasonique selon une condition ultrasonique définie, lorsque cette énergie est dirigée localement sur une partie du coeur.

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