Local drug delivery using photosensitizer-mediated and...

Details Local drug delivery using photosensitizer-mediated and... Local drug delivery using photosensitizer-mediated and...

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 31/555 (2006.01) A61K 41/00 (2006.01) A61N 5/06 (2006.01)

Patent

CA 2397333

The invention relates to the site specific delivery of drugs in an organism. The described methods facilitate the delivery of a therapeutic or diagnostic drug by increasing vascular permeability in a site specific manner. Vascular permeability is enhanced in the disclosed methods by using a combination of a photosensitizer and radiation applied to a site of interest.

Cette invention a trait à une administration de médicament à spécificité de site. Le procédé selon l'invention facilite l'administration d'un agent thérapeutique ou diagnostique par augmentation de la perméabilité vasculaire d'un site spécifique. On augmente la perméabilité vasculaire en associant un agent photosensibilisant et un rayonnement que l'on applique sur le site concerné.

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