A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 31/16 (2006.01) A61F 2/90 (2006.01) A61K 9/00 (2006.01) A61K 31/427 (2006.01) A61K 31/4439 (2006.01) A61P 5/50 (2006.01) A61P 9/00 (2006.01)
Patent
CA 2639640
Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the prevention of thrombosis. The drugs, agents, and/or compounds may also be utilized to treat specific disorders, including vulnerable plaque, and athereosclerosis in type 2 diabetic patients. Therapeutic agents may also be delivered to the region of a disease site. In regional delivery, liquid formulations may be desirable to increase the efficacy and deliverability of the particular drug. Also, the devices may be modified to promote endothelialization. Various materials and coating methodologies may be utilized to maintain the agents or compounds on the medical device until delivered and positioned. In addition, the devices utilized to deliver the implantable medical devices may be modified to reduce the potential for damaging the implantable medical device during deployment. In addition, various polymer combinations may be utilized to control the elution rates of the therapeutic drugs, agents and/or compounds from the implantable medical devices.
Falotico Robert
Luk Andrew Sheung-King
Parker Theodore L.
Zhao Jonathon Z.
Zhao Lei
Cordis Corporation
Sim & Mcburney
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