Locally administrable therapeutic composition for...

A - Human Necessities – 61 – K

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A61K 31/195 (2006.01) A61K 9/00 (2006.01) A61K 47/04 (2006.01) A61K 47/30 (2006.01)

Patent

CA 1325382

TITLE OF THE INVENTION A locally administrable therapeutic composition for inflammatory disease ABSTRACT OF THE DISCLOSURE This invention relates to a locally administrable therapeutic composition for inflammatory disease which is characterized by comprising benzoylphenetylacetic acid of the formula Image (wherein R is a hydrogen or halogen atom), or a salt thereof, or the hydrate of said acid or salt, as active ingredient. The ophthalmic composition according to the invention can treat effectively inflammatory eye disease by topical application, is not irritant to the eye, and has a superior effect to conventional drugs of the same or similar type. The aqueous composition prepared in accordance with this invention has an excellent stability and can be used advantageously as a nasal or otic composition as well as ophthalmic one in the treatment of inflammatory otic or nasal disease.

589025

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