Long acting erythropoietins that maintain tissue protective...

Details Long acting erythropoietins that maintain tissue protective... Long acting erythropoietins that maintain tissue protective...

A - Human Necessities

61

K

A61K 38/18 (2006.01) A61K 38/16 (2006.01) A61K 38/22 (2006.01) A61K 47/48 (2006.01) C07K 1/10 (2006.01) C07K 14/505 (2006.01)

Patent

CA 2497960

Methods for increasing the hematocrit of an individual while maintaining the tissue protective activities of endogenous through the administration of a pharmaceutical compound containing chemically modified long acting erythropoietin. Also disclosed are the new chemically modified long acting erythropoietins, methods of producing the chemically modified long acting erythropoietins, and compositions comprising the chemically modified long acting erythropoietins.

L'invention porte sur des procédés visant à augmenter le taux des hématocrites chez un individu tout en maintenant l'activité protectrice du tissu d'une érythropoïétine endogène en administrant un composé pharmaceutique contenant une érythropoïétine à action longue modifiée chimiquement. L'invention porte également sur de nouvelles érythropoïétines à action longue, modifiées chimiquement, sur leurs procédés de production et sur les compositions les comprenant.

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