Long acting granular pharmaceutical composition

Details Long acting granular pharmaceutical composition Long acting granular pharmaceutical composition

A - Human Necessities

61

K

167/164

A61K 9/52 (2006.01) A61K 9/50 (2006.01)

Patent

CA 2038400

ABSTRACT OF THE DISCLOSURE A long acting granular composition which comprises: (a) a fine particulate nucleus composed of a water-insoluble substance; (b) a drug layer containing a drug which is difficult to prepare in long acting form and a non-swellable entero-soluble base; and (c) a drug-release controlling film containing a drug-release controlling material and en entero- soluble base is disclosed. The long acting granular composition of the present invention has a very satisfactory drug-release pattern and is free from the risk of abrupt disintegration in the digestive tract. - 21 -

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