A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/566 (2006.01)
Patent
CA 2580264
The present invention provides sustained release formulations of estradiol metabolites whereby the in vivo pharmacokinetics are manipulated by a method selected from the group consisting of chemical modification, crystal packing formation, particle size or a combination thereof. Such compositions are useful in the long-term treatment of a wide variety of diseases.
La présente invention porte sur des formulations à libération prolongée de métabolites d'estradiol. Dans ces formulations, les métabolites sont manipulés par pharmacocinétique in vivo selon un procédé sélectionné dans le groupe comprenant la modification chimique, la formation de paquets de cristaux, la grosseur de particule ou une combinaison de celles-ci. Ces compositions sont utiles dans le traitement à long terme d'une large plage de maladies.
Allison S. Dean
Allison S. Dean
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Pr Pharmaceuticals Inc.
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