Long-acting polypeptides and methods of producing and...

Details Long-acting polypeptides and methods of producing and... Long-acting polypeptides and methods of producing and...

C - Chemistry, Metallurgy

07

K

C07K 19/00 (2006.01) A61K 38/16 (2006.01) A61K 38/18 (2006.01) A61K 38/22 (2006.01) A61K 38/27 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C07K 14/505 (2006.01) C07K 14/555 (2006.01) C07K 14/59 (2006.01) C07K 14/605 (2006.01) C07K 14/61 (2006.01) C12N 15/16 (2006.01) C12N 15/18 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2641342

A polypeptide and polynucleotides encoding same comprising at least two carboxy-terminal peptide (CTP) sequences of chorionic gonadotropin attached to a peptide-of-interest are disclosed. Pharmaceutical compositions comprising the polypeptide and polynucleotides of the invention and methods of using same are also disclosed.

L'invention concerne un polypeptide et des polynucléotides codant pour lui comprenant au moins deux séquences peptidiques carboxyterminales (CTP) de la gonadotrophine chorionique liées à un peptide d'intérêt. Elle concerne également des compositions pharmaceutiques comprenant le polypeptide et les polynucléotides de l'invention, ainsi que des procédés pour les utiliser.

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