Long acting preparation of cefalexin for effective...

Details Long acting preparation of cefalexin for effective... Long acting preparation of cefalexin for effective...

A - Human Necessities

61

K

167/187

A61K 31/545 (2006.01) A61K 9/50 (2006.01)

Patent

CA 1085296

LONG ACTING PREPARATION OF CEFALEXIN FOR EFFECTIVE TREATMENTS OF BACTERIAL INFECTION SENSITIVE TO CEFALEXIN ABSTRACT A cefalexin preparation coated with a coating layer the solu- bility of which layer is pH-dependent and dissolves at upper intes- tine is preferably administered concurrently with a normal (plain, quick-releasing) cefalexin preparation. The coated preparation is preferably coated, in the particle form and when administered orally, exists in the particle form at stomach. Preferably, the coating layer is made from coating base material having dissolution pH of from 5.5 to 6.5, and the ratio in potency of the coated cefalexin to the normal cefalexin is between 15 : 85 and 60 : 40. The coated cefalexin and the normal cefalexin can be composed to a pharmaceutical preparation preferably in a unit-dosage form, e.g. capsules, tablets or particles or in strip-packages.

276514

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