Long-acting treatment by slow-release delivery of antisense...

A - Human Necessities – 61 – K

Patent

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A61K 48/00 (2006.01) A61K 9/16 (2006.01) A61K 31/70 (2006.01) A61K 47/48 (2006.01) C07H 21/00 (2006.01)

Patent

CA 2160877

Alteration of gene expression in animals by introduction of a biodegradable microparticle composition of an antisense oligodeoxyri- bonucleotide within a biodegradable polymeric matrix into a target cell is provided. Methods for the controlled delivery of the compositions are provided.

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