Long-lasting adhesive antifungal suppositories

Details Long-lasting adhesive antifungal suppositories Long-lasting adhesive antifungal suppositories

A - Human Necessities

61

K

167/160

A61K 9/02 (2006.01) A61K 9/00 (2006.01) A61K 35/66 (2006.01)

Patent

CA 1255225

ABSTRACT LONG-LASTING ADHESIVE ANTIFUNGAL SUPPOSITORIES Antifungal suppositories are provided which preferably include nystatin as the antifungal agent, together with a hydrocolloid, such as sodium carboxymethylcellulose or hydroxypropyl- methylcellulose and a low melting suppository base. The antifungal suppositories of the inven- tion function by melting at body temperature to release the hydrocolloid and antifungal agent which adhere to the vaginal membrane so that a uniform distribution of antifungal agent is retained at the site of infection.

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