Long lasting exendin-4

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/575 (2006.01) A61K 38/22 (2006.01) A61P 3/10 (2006.01) C07K 14/605 (2006.01) C07K 14/765 (2006.01) C07K 19/00 (2006.01)

Patent

CA 2501421

Modified insulinotropic peptides are disclosed. The modified insulinotropic peptides are capable of forming a peptidase stabilized insulinotropic peptide. The modified insulinotropic peptides are capable of forming covalent bonds with one or more blood components to form a conjugate. The conjugates may be formed in vivo or ex vivo. The modified peptides are administered to treat humans with diabetes and other related diseases.

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