C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/605 (2006.01) A61K 38/26 (2006.01) A61P 3/08 (2006.01) C07K 14/575 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2363712
Modified insulinotropic peptides are disclosed. The modified insulinotropic peptides are capable of forming a peptidase stabilized insulinotropic peptide. The modified insulinotropic peptides are capable of forming covalent bonds with one or more blood components to form a conjugate. The conjugates may be formed in vivo or ex vivo. The modified peptides are administered to treat humans with diabetes and other related diseases.
L'invention concerne des peptides insulinotropes modifiés, capables de former un peptide insulinotrope stabilisé en peptidase, et de former des liaisons covalentes avec un ou plusieurs composants sanguins de manière à constituer un conjugué. Les conjugués peuvent être constitués in vivo ou ex vivo. Les peptides modifiés considérés sont administrés aux personnes qui nécessitent un traitement pour le diabète et autres maladies connexes.
Bridon Dominique P.
Ezrin Alan M.
Holmes Darren L.
L'archeveque Benoit
Leblanc Anouk
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Conjuchem Biotechnologies Inc.
Conjuchem Inc.
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