Long pentraxin ptx3 functional derivatives for preparing an...

Details Long pentraxin ptx3 functional derivatives for preparing an... Long pentraxin ptx3 functional derivatives for preparing an...

C - Chemistry, Metallurgy

07

K

C07K 14/195 (2006.01) A61K 39/102 (2006.01) C07K 14/47 (2006.01) C07K 14/475 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2475526

The invention described herein refers to derivatives of the long pentraxin PTX3 with the sequence indicated in the text, capable of binding to the membranes of inactivated tumour cells. The inactivated tumour cells, bearing on their surface a derivative of PTX3 are used to prepare an autologous vaccine for the treatment of tumours.

L'invention se rapporte à des dérivés d'une longue pentraxine PTX3 ayant la séquence indiquée dans le texte et aptes à se lier aux membranes de cellules tumorales inactivées. Lesdites cellules, portant sur leur surface un dérivé de PTX3, sont utilisées pour préparer un vaccin autologue en vue du traitement de tumeurs.

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