Long-term stable pharmaceutical preparation having the...

Details Long-term stable pharmaceutical preparation having the... Long-term stable pharmaceutical preparation having the...

A - Human Necessities

61

K

A61K 9/12 (2006.01) A61K 31/21 (2006.01)

Patent

CA 2718345

The invention relates to a pharmaceutical composition containing the active ingredient glycerol trinitrate having improved storage stability in a container. The improved storage stability is achieved by adding a substance absorbing protons, which is added to the composition, or applied to the surfaces of the container coming in contact with the product. The composition is preferably filled into a plastic bottle having a spray pump.

L'invention concerne une composition pharmaceutique, contenant le principe actif trinitrate de glycérol, présentant une stabilité améliorée au stockage dans un récipient. La stabilité améliorée au stockage est réalisée grâce à l'addition d'une substance absorbant les protons, qui est ajoutée à la composition ou qui est appliquée sur les surfaces du récipient en contact avec le produit. De préférence, la composition est transvasée dans un flacon en matière plastique, avec une pompe pour aérosol.

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