Long term sustained release pharmaceutical composition...

A - Human Necessities – 61 – K

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A61K 31/66 (2006.01) A61P 19/10 (2006.01)

Patent

CA 2673058

Pharmaceutical compositions for long-term sustained release of bisphosphonate drugs are provided. In one embodiment, the composition includes an aqueous suspension of a solid which includes a salt of a bisphosphonate drug and a salt of pentavalent phosphorus oxoacid. The compositions can be used to treat a variety of bone diseases, including osteoporosis.

L'invention concerne des compositions pharmaceutiques permettant la libération prolongée de longue durée de biphosphonates. Dans un mode de réalisation, la composition comprend une suspension aqueuse d'un solide renfermant un sel de biphosphonate et un sel d'oxoacide phosphoreux pentavalent. Les compositions de l'invention peuvent être utilisées pour traiter une variété de maladies osseuses, y compris l'ostéoporose.

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