Loratadine for use as an antiarrhythmic

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/445 (2006.01) A61K 31/4545 (2006.01)

Patent

CA 2276324

Disclosed is a pharmaceutical composition for treating arrhythmias including atrial fibrillation in mammals using loratadine, i. e., ethyl 4-(8-chloro-5,6-dihydro-11H- benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidine-carboxylate of the formula I Image , or a metabolite thereof, e. g., descarboethoxycarbonyl loratadine.

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