A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4709 (2006.01) A61K 9/08 (2006.01) A61K 47/10 (2006.01) A61K 47/30 (2006.01) A61K 47/38 (2006.01) A61P 17/00 (2006.01) A61P 31/04 (2006.01)
Patent
CA 2615912
It is intended to provide a lotion preparation which exerts an excellent antibacterial effect, is excellent in the stability of active ingredient and does not contain an additive having a safety problem. The lotion preparation contains (a) 1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)-3-pyridyl]-4- oxo-1,4-dihydro-3-quinolinecarboxylic acid and/or a pharmaceutically acceptable salt thereof, (b) a lower alcohol, (c) a water-soluble polymer and (d) a polyhydric alcohol and the pH of the preparation is in the range of 9 to 12.
La présente invention a pour objet une préparation sous forme de lotion qui présente un excellent effet antibactérien, dont la stabilité du principe actif est excellente et qui ne contient pas d'adjuvant présentant un problème de santé ou de sécurité. La préparation sous forme de lotion contient (a) de l'acide 1-cyclopropyl-8-méthyl-7-[5-méthyl-6-(méthylamino)-3-pyridyl]-4-oxo-1,4-dihydro-3-quinolinecarboxylique et/ou un sel de qualité pharmaceutique dudit acide, (b) un alcool inférieur, (c) un polymère hydrosoluble et (d) un polyol, et le pH de la préparation est compris entre 9 et 12.
Hirota Tsuyoshi
G. Ronald Bell & Associates
Maruho Co. Ltd.
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