A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/165 (2006.01) A61K 9/70 (2006.01) A61K 47/08 (2006.01) A61K 47/24 (2006.01) A61P 29/00 (2006.01) A61K 47/38 (2006.01)
Patent
CA 2602832
Described here are patches and methods for treating neuropathic pain. In some variations, the neuropathic pain-relieving patch comprises capsaicin or a capsaicin analog, wherein the concentration of the capsaicin or capsaicin analog is less than 1% by weight, and a penetration enhancer, wherein the patch is capable of relieving neuropathic pain over a sustained period of time. The penetration enhancer may be any suitable penetration enhancer. The patches may also include oils, viscosity increasing agents, and the like. In some variations, the pain-relieving patches comprise capsaicin, or an, wherein the concentration of the capsaicin or analog is less than 1%, and a penetration enhancer, whereby delivery of capsaicin from the patch continues for at least an hour, and whereby a single use of the patch provides a therapeutic benefit for at least one month, two months, or three months. Methods for treating neuropathic pain are also described.
L'invention porte sur des timbre transdermique à faible concentration de capsaïcine et des méthodes de traitement des douleurs neuropathiques. Dans certaines variantes le timbre, qui permet d'atténuer les douleurs pendant une période importante, comporte de la capsaïcine ou l'un de ses analogues à une concentration inférieure à 1 % en poids, un renforceur de pénétration de type usuel et éventuellement des huiles, des viscosifiants, et analogues. Dans d'autres variantes, le timbre comporte de la capsaïcine ou l'un de ses analogues à une concentration inférieure à 1 % et un renforceur de pénétration, et la libération de la capsaïcine dure au moins une heure, une seule utilisation du timbre pouvant assurer un bénéfice thérapeutique sur au moins un, deux ou trois mois. L'invention porte également sur des méthodes de traitement des douleurs neuropathiques.
Borden Ladner Gervais Llp
Neurogesx Inc.
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