A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/32 (2006.01) A61K 9/00 (2006.01) A61K 33/40 (2006.01) A61P 15/02 (2006.01) A61K 47/10 (2006.01) A61K 47/14 (2006.01) A61K 47/38 (2006.01)
Patent
CA 2465133
The invention relates to a pharmaceutical vaginal composition for treating or preventing vaginal infections. The composition includes a synergistic mix of a bioadhesive, extended release formulation that decreases the pH and that contains a peroxide in an amount sufficient to increase oxygen concentration without sterilizing the vagina or substantially killing the normally-desired local vaginal flora. The invention also relates to a method of treating or preventing vaginal infections in a patient comprising inserting vaginally an amount of the pharmaceutical vaginal composition in an amount sufficient to decrease the pH and increase oxygene concentration without sterilizing the vagina or substantially killing the normally-desired local vaginal flora.
L'invention a trait à une composition pharmaceutique conçue pour traiter ou prévenir des infections vaginales. Ladite composition comprend un mélange synergique d'une préparation bioadhésive et à libération prolongée, qui réduit le pH et contient une quantité de péroxyde suffisante pour augmenter la concentration d'oxygène sans stériliser le vagin ou détruire sensiblement la flore vaginale locale normalement souhaitée. L'invention concerne également une méthode permettant de traiter ou de prévenir des infections vaginales chez un patient, consistant à introduire par voie vaginale une quantité de ladite composition pharmaceutique suffisante pour réduire le pH et augmenter la concentration d'oxygène sans stériliser le vagin ou détruire sensiblement la flore vaginale locale normalement souhaitée.
Bologna William J.
Levine Howard L.
Columbia Laboratories (bermuda) Limited
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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