Low dose pharmaceutical powders for inhalation

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/72 (2006.01) A61K 9/14 (2006.01) A61M 15/00 (2006.01)

Patent

CA 2528064

The invention relates to a method of delivering an agent to the pulmonary system of a compromised patient, in a single breath-activated step, comprising administering a particle mass comprising an agent from an inhaler containing less than 5 milligrams of the mass, wherein at least about 50% of the mass in the receptacle is delivered to the pulmonary system of a patient. The invention also relates to receptacles containing the particle mass and the inhaler for use therein.

La présente invention concerne un procédé permettant de faire parvenir au système pulmonaire d'un patient en détresse un agent pharmaceutique en une opération déclenchée par une seule respiration. Il s'agit d'administrer une masse de particules comprenant un agent en utilisant un inhalateur contenant moins de 5 mg de cette masse dont au moins 50 % environ arrivera au système pulmonaire du patient. L'invention concerne également, d'une part des capsules pressurisées contenant la masse de particules, et d'autre part l'inhalateur à utiliser avec ces capsules.

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