Low estrogen oral contraceptives

Details Low estrogen oral contraceptives Low estrogen oral contraceptives

A - Human Necessities

61

K

A61K 31/565 (2006.01) A61K 31/57 (2006.01)

Patent

CA 2057528

Disclosed is a contraceptive regimen, and method of using the regimen, comprising 24 daily sequential dosage units of: a first phase comprising about 7 to 9 sepa- rate first dosage units containing a progestogen at a daily dosage equivalent in progestogenic activity to 100 µg desogestrel and an estrogen at a daily dosage equiva- lent in estrogenic activity to 25 µg ethinyl estradiol ("EE"). A second phase of 7 to 9 second dosage units, each of the second dosage units containing a progestogen equivalent to 125 µg desogestrel and an estrogen equiva- lent to 20 µg EE. A third phase of 7 to 9 third dosage units, each unit containing a progestogen equivalent to 150 µg desogestrel and an estrogen equivalent to 20 µg EE. The kit generally has 28 daily dosage units wherein four of the daily dosage units contain no contraceptive steroid, or, alternatively, have only 24 dosage units with a four day "pill-free" period. The fourth phase may also be four dosage units containing a progestogen equivalent to 25 - 35 µg desogestrel.

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