Low flush niacin formulation

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/455 (2006.01) A61K 9/22 (2006.01) A61K 47/12 (2006.01) A61K 47/32 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2569776

The invention relates to an extended-release matrix formulation capable of being directly compressed into tablets comprising niacin, a release-retarding agent, and other excipients. The resulting tablets of the invention demonstrate favorable release characteristics and a reduction in the severity, duration and incidences of cutaneous flushing commonly associated with niacin treatment.

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