Low flux transdermal potent drug delivery system

Details Low flux transdermal potent drug delivery system Low flux transdermal potent drug delivery system

A - Human Necessities

61

K

A61K 9/70 (2006.01) A61K 31/56 (2006.01) A61K 31/565 (2006.01)

Patent

CA 2169164

Matrix-type transdermal drug delivery devices for administering potent steroids such as ethinyl estradiol at a low flux steady-state rate over a multi-day period comprising a laminate of: (a) an occlusive backing layer and (b) a matrix layer of the drug completely dissolved at a loading of below 0.5 % by weight in a 2-ethylhexyl acrylate copolymer.

Dispositif d'administration transdermique de médicament de type matrice servant à administrer des stéroïdes puissants, tels qu'éthinyle estradiol, selon un débit faible et constant sur une période de plusieurs jours. Ledit dispositif est composé d'un stratifié comprenant: (a) une couche de support occlusive et (b) une couche matrice contenant le médicament entièrement dissous selon une charge inférieure à 0,5 % en poids dans un copolymère d'acrylate de 2-éthylhexyle.

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