Low hygroscopic aripiprazole drug substance and processes...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/20 (2006.01) A61J 3/10 (2006.01) A61K 31/496 (2006.01) A61K 9/16 (2006.01)

Patent

CA 2713466

The present invention provides low hygroscopic forms of aripiprazole and processes for the preparation thereof which will not convert to a hydrate or lose their original solubility even when a medicinal preparation containing the anhydrous aripiprazole crystals is stored for an extended period.

La présente invention a pour objet des formes faiblement hygroscopiques d'aripiprazole et des procédés pour leur préparation qui ne les convertiront pas en un hydrate ou ne leur feront pas perdre leur solubilité originale, même quand une préparation médicale contenant les cristaux d'aripiprazole anhydre sont entreposés pendant une longue période.

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