Low hygroscopic aripiprazole drug substance and processes...

Details Low hygroscopic aripiprazole drug substance and processes... Low hygroscopic aripiprazole drug substance and processes...

C - Chemistry, Metallurgy

07

D

C07D 215/22 (2006.01) A61K 31/496 (2006.01) C07D 401/12 (2006.01) A61J 3/10 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2689051

The present invention provides low hygroscopic forms of aripiprazole and processes for the preparation thereof which will not convert to a hydrate or lose their original solubility even when a medicinal preparation containing the anhydrous aripiprazole crystals is stored for an extended period.

La présente invention porte sur des formes faiblement hygroscopiques de l'aripiprazole et sur des procédés visant la préparation de celles-ci. Ces formes ne se transforment pas en hydrates et ne perdent pas leur solubilité d'origine même lorsque la préparation médicinale contenant des cristaux d'aripiprazole anhydres est conservée pendant une longue période.

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