Low hygroscopic aripiprazole drug substance and processes...

Details Low hygroscopic aripiprazole drug substance and processes... Low hygroscopic aripiprazole drug substance and processes...

C - Chemistry, Metallurgy

07

D

C07D 215/22 (2006.01) A61K 31/496 (2006.01) C07D 401/12 (2006.01) A61J 3/10 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2688915

The present invention provides low hygroscopic forms of aripiprazole and processes for the preparation thereof which will not convert to a hydrate or lose their original solubility even when a medicinal preparation containing the anhydrous aripiprazole crystals is stored for an extended period.

La présente invention concerne des formes faiblement hygroscopiques de l'aripiprazole et les procédés permettant de produire ces formes, lesquelles ne seront pas converties en hydrates et ne perdront pas leur solubilité originelle, même lorsqu'une préparation médicinale contenant des cristaux d'aripiprazole anhydre est entreposée pendant une longue période.

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