Low hygroscopic aripiprazole drug substance and processes...

Details Low hygroscopic aripiprazole drug substance and processes... Low hygroscopic aripiprazole drug substance and processes...

C - Chemistry, Metallurgy

07

D

C07D 215/22 (2006.01) A61K 9/20 (2006.01) A61K 31/496 (2006.01) C07D 401/12 (2006.01) A61J 3/10 (2006.01)

Patent

CA 2689052

The present invention provides low hygroscopic forms of aripiprazole and processes for the preparation thereof which will not convert to a hydrate or lose their original solubility even when a medicinal preparation containing the anhydrous aripiprazole crystals is stored for an extended period.

La présente invention fournit des formes peu hygroscopiques d'aripiprazole et des procédés pour la préparation de celles-ci, procédés qui ne convertissent pas la substance en hydrate et qui ne lui enlèvent pas sa solubilité originale, même lorsqu'une préparation médicinale contenant des cristaux anhydres d'aripiprazole est entreposée pendant une période prolongée.

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