Low hygroscopic aripiprazole drug substance and processes...

Details Low hygroscopic aripiprazole drug substance and processes... Low hygroscopic aripiprazole drug substance and processes...

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 9/20 (2006.01) A61K 31/496 (2006.01) A61P 25/00 (2006.01) A61P 25/18 (2006.01) A61P 25/28 (2006.01) C07D 215/22 (2006.01)

Patent

CA 2426921

The present invention provides low hygroscopic forms of aripiprazole and processes for the preparation thereof which will not convert to a hydrate or lose their original solubility even when a medicinal preparation containing the anhydrous aripiprazole crystals is stored for an extended period.

L'invention concerne des formes faiblement hygroscopiques d'aripiprazole et des méthodes de préparation associées. Les réalisations selon l'invention ne se transforment pas en un hydrate et elles ne perdent pas leur solubilité originelle, même lorsqu'une préparation médicamenteuse contenant les cristaux d'anhydride d'aripiprazole est stockée pendant longtemps.

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