Low-molecular heparin modification and remedy for skin ulcer

C - Chemistry – Metallurgy – 08 – B

Patent

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C08B 37/10 (2006.01) A61K 31/727 (2006.01) C08B 37/00 (2006.01)

Patent

CA 2310422

A heparin derivative having an excellent effect of remedying skin ulcer and a skin ulcer remedy containing the same. The heparin derivative refers to a heparin modification and/or a low-molecular heparin modification and serves as a skin ulcer remedy after being deprived of the anticoagulant activity while retaining the ability to bind to cell growth factors, cytokines or cell adhesion factors.

L'invention concerne un dérivé d'héparine présentant un excellent effet remédiant à l'ulcère de la peau et un remède contre l'ulcère de la peau le contenant. Le dérivé d'héparine a trait à une modification de l'héparine et/ou une modification de l'héparine de faible masse moléculaire et il sert de remède contre l'ulcère de la peau après avoir été dépossédé de l'activité d'anticoagulant tout en conservant la capacité de se fixer à des facteurs de croissance cellulaire, des cytokines ou des facteurs d'adhésion cellulaire.

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