Low molecular weight gtpase rhot

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/09 (2006.01) A61K 38/46 (2006.01) A61K 48/00 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01) A61P 43/00 (2006.01) C12N 9/16 (2006.01) C12N 15/52 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2462858

Low molecular weight GTPase RhoT having the amino acid sequence represented by SEQ ID NO:1 or an amino acid sequence derived from this amino acid sequence by the substitution, deletion, addition or insertion of one or more amino acids; its gene; and drugs containing the same. RhoT has an excellent effect of forming and/or extending neurites.

La présente invention concerne la GTpase RhoT de faible poids moléculaire possédant la séquence d'amino-acides représentée par SEQ ID NO: 1 ou une séquence d'amino-acides dérivée de cette séquence d'amino-acides par la substitution, la délétion, l'addition ou l'introduction d'un ou de plusieurs amino-acides. Cette invention concerne aussi son gène et des médicaments contenant cette GTpase. Cette GTpase RhoT à pour excellent effet de former et/ou de développer les neurites.

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