Low molecular weight heparins including at least one...

Details Low molecular weight heparins including at least one... Low molecular weight heparins including at least one...

C - Chemistry, Metallurgy

08

B

C08B 37/10 (2006.01) A61K 31/715 (2006.01)

Patent

CA 2678168

The invention relates to low molecular-weight heparins including at least one covalent bond with biotin or a biotin derivative at their reduction end, to a method for preparing the same and to the use thereof in therapy, and to a method implementing avidine or streptavidine for neutralising said biotinylated low molecular-weight heparins.

La présente invention concerne des héparines de bas poids moléculaire présentant au moins une liaison covalente avec la biotine ou un dérivé de la biotine au niveau de leur extrémité réductrice, leur procédé de préparation et leur utilisation en thérapeutique, ainsi qu'un procédé mettant en AEuvre l'avidine ou la streptavidine et permettant de neutraliser lesdites héparines de bas poids moléculaire biotinylées.

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