Low molecular weight thyroid stimulating hormone receptor...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 239/91 (2006.01) A61K 31/517 (2006.01) A61K 49/00 (2006.01) A61P 35/00 (2006.01) C07D 405/06 (2006.01)

Patent

CA 2741030

Disclosed are oxo-hydroquinazolines of formula I that are useful as selective TSHR agonists. The compounds may be used for detecting or treating thyroid cancer, or treating a bone degenerative disorder.

La présente invention concerne des oxo-hydroquinazolines de formule I utiles en tant qu'agonistes sélectifs du TSHR. Les composés de linvention peuvent être utilisés pour détecter ou traiter un cancer de la thyroïde, ou pour traiter un trouble dégénératif osseux.

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