Low-oxygen fluorocarbon as an agent for ophthalmology

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/02 (2006.01) A61K 9/00 (2006.01) A61K 31/025 (2006.01) A61K 47/06 (2006.01)

Patent

CA 2266091

The present invention concerns fluorocarbons for use in ophthalmology. Fluorocarbons disclosed in the prior art can only be left in the eye for a limited period of time because they cause damage to the retina or intraocular structure. The present invention provides an oxygen-fluorocarbon mixture having a dissolved oxygen content of less than 6% by volume, which can be used as an ophthalmological agent for longer periods of time than conventional fluorocarbons, with little or no damage to the retina or intraocular structures. The invention also provides a process for preparing the oxygen-fluorocarbon mixture. In one embodiment, up to 20% by volume of a second gas, such as carbon dioxide or nitric oxide, is combined with the oxygen-fluorocarbon mixtures.

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