Low polydispersity poly-hema compositions

C - Chemistry – Metallurgy – 08 – L

Patent

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Details

C08L 33/10 (2006.01) B29D 11/00 (2006.01) C08F 2/38 (2006.01) C08F 20/28 (2006.01) C08J 3/28 (2006.01) C08L 33/02 (2006.01) C08L 33/12 (2006.01) C08L 33/26 (2006.01) C08L 39/06 (2006.01) C08L 83/04 (2006.01) G02B 1/04 (2006.01)

Patent

CA 2478307

The present invention relates to compositions comprising poly-HEMA having a peak molecular weight between about 25,000 and about 100,000, preferably between 25,000 and 80,000 and a polydispersity of less than about 2 to less than about 3.8 respectively and covalently bonded thereon, at least one cross- linkable functional group. The present invention further relates to low polydispersity poly-HEMA suitable for making the crosslinkable prepolymers, processes for functionalizing and purifying said poly-HEMA to form said crosslinkable prepolymers, viscous solutions made from said crosslinkable prepolymers, hydrogels made from said viscous solutions and articles made from said crosslinkable polymers, hydrogels and viscous solutions.

L'invention concerne des compositions comprenant du poly-HEMA présentant un poids moléculaire maximum compris entre environ 25000 et environ 100000, de préférence entre 25000 et 80000; et une polydispersité respectivement comprise entre environ moins de 2 et environ moins de 3,8; au moins un groupe fonctionnel réticulable étant lié à celles-ci par covalence. L'invention concerne en outre du poly-HEMA de faible polydispersité approprié à la production de prépolymères réticulables; des procédés de fonctionnalisation et de purification dudit poly-HEMA afin de former lesdits prépolymères réticulables; des solutions visqueuses obtenues à partir desdits prépolymères réticulables; des hydrogels obtenus à partir desdites solutions visqueuses et des produits obtenus à partir desdits polymères réticulables, hydrogels, et solutions visqueuses.

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