Low temperature drying methods for forming drug-containing...

A - Human Necessities – 61 – K

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A61K 9/48 (2006.01) A61J 3/07 (2006.01) A61K 47/30 (2006.01) A61L 27/54 (2006.01)

Patent

CA 2572106

The present invention relates to a process for reducing solvent contents in drug-containing polymeric compositions. Specifically, the solvent contents in the drug- containing polymeric compositions are first reduced by one or more conventional drying methods, to a range from about 0.5 wt% to about 10 wt% of the total weight of the polymeric composition. Subsequently, the drug-containing polymeric compositions are further treated by one or more low temperature (i.e., having processing temperatures of less than 60°C) drying methods for further reduction of the solvent content to less than 10,000 ppm.

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