Lowering of blood uric acid levels

Details Lowering of blood uric acid levels Lowering of blood uric acid levels

A - Human Necessities

61

K

A61K 31/50 (2006.01)

Patent

CA 2048235

Certain derivatives of oxophthalazinyl acetic acids of the formula Image ...1 wherein R1 is hydroxy or a prodrug group, and R2 and R3 are independently hydrogen, fluoro, chloro or trifluoromethyl, except that R2 and R3 are not both hydrogen, or a pharmaceutically acceptable base addition salt of a compound of formula I wherein R1 is hydroxy, are capable of lowering blood uric acid levels in mammals. These oxophthalazinyl acetic acid derivatives are for instance useful for treating gout and gouty arthritis in a mammal.

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