A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/661 (2006.01)
Patent
CA 2754551
Disclosed are compounds according to formula (I) as well as pharmaceutical compositions which include those compounds. Also disclosed are methods of using such compounds, which have activity as agonists or as antagonists of LPA receptors; such methods including treating cancer, producing radioprotection and/or radiomitigation, enhancing cell proliferation, treating a wound, treating apoptosis or preserving or restoring function in a cell, tissue, or organ, culturing cells, preserving organ or tissue function, and treating a dermato logical condition.
L'invention concerne des composés représentés par la formule (1) ainsi que des compositions pharmaceutiques comprenant ces composés. L'invention concerne également des méthodes utilisant les composés qui présentent une activité d'agonistes ou d'antagonistes. Lesdites méthodes consistent à traiter le cancer, produire une radioprotection et/ou une radioatténuation, améliorer la prolifération cellulaire, traiter une plaie, traiter l'apoptose ou préserver ou restaurer une fonction dans une cellule, un tissu ou un organe, cultiver des cellules, préserver une fonction d'organe ou de tissu et traiter un état dermatologique.
Rxbio Inc.
Smart & Biggar
LandOfFree
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