Luminescent 1-hydroxy-2-pyridinone chelates of lanthanides

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 213/89 (2006.01) C07C 235/84 (2006.01) C07D 239/52 (2006.01) C07D 309/40 (2006.01) G01N 33/52 (2006.01)

Patent

CA 2659251

The present invention provides luminescent complexes between a lanthanide ion and an organic ligand which contains 1,2-hydroxypyridinone units. The complexes of the invention are stable in aqueous solutions and are useful as molecular probes, for example in medical diagnostics and bioanalytical assay systems. The invention also provides methods of using the complexes of the invention.

La présente invention concerne des complexes luminescents entre un ion de lanthanide et un ligand organique qui contient des motifs 1,2-hydroxypyridinone. Les complexes de l'invention sont stables dans des solutions aqueuses et sont utiles en tant que sondes moléculaires, par exemple dans un diagnostic médical et des systèmes de dosage bio-analytique. L'invention concerne également des procédés utilisant les complexes de l'invention.

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