C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 229/76 (2006.01) A61K 51/04 (2006.01) C07D 241/20 (2006.01) C07D 241/40 (2006.01) C07D 311/16 (2006.01) C09K 11/08 (2006.01)
Patent
CA 2578030
Some embodiments of the present invention may be said to be directed to metal complexes of Formula I, wherein at least one of X1, X2, X3, R1, R2, R3, R4 and R5 is what may be characterized as an antenna capable of providing (e.g., absorbing and/or emitting) an appropriate electromagnetic signal. Some embodiments of the present invention are directed to ligands corresponding to metal complexes of Formula I. Some embodiments of the invention are directed to methods of determining renal function using at least one metal complex of Formula I.
La présente invention a pour objet des complexes métalliques de Formule I, où au moins l~un des substituants X1, X2, X3, R1, R2, R3, R4 et R5 peut être désigné comme étant une antenne réglée sur un signal électromagnétique approprié, c'est-à-dire capable d'absorber ou d'émettre ledit signal. La présente invention a également pour objet des ligands intervenant dans les complexes métalliques de Formule I, ainsi que des méthodes de surveillance et d~évaluation des fonctions rénales utilisant au moins l~un des complexes métalliques de Formule I.
Dorshow Richard B.
Moore Dennis A.
Rajagopalan Raghavan
Mallinckrodt Inc.
Mallinckrodt Llc
Osler Hoskin & Harcourt Llp
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