Lupus antibodies for passive immunotherapy of hiv/aids

Details Lupus antibodies for passive immunotherapy of hiv/aids Lupus antibodies for passive immunotherapy of hiv/aids

C - Chemistry, Metallurgy

07

K

C07K 16/10 (2006.01) A61K 39/395 (2006.01) A61P 31/18 (2006.01) C12P 21/08 (2006.01)

Patent

CA 2520382

Disclosed are monoclonal antibodies and antibody fragments which recognize antigens encoded by HERV DNA sequences, and methods for production, including recombinant antibody fragments derived from lymphoid cells of lupus patients that make antibodies which neutralize HIV.

L'invention concerne des anticorps monoclonaux et des fragments d'anticorps qui reconnaissent des antigènes codés par des séquences ADN HERV, ainsi que des procédés de production associés. Lesdits anticorps comprennent des fragments d'anticorps de recombinaison dérivés de cellules lymphoïdes de patients atteints de lupus qui fabriquent des anticorps neutralisant le virus VIH.

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