Lupus assay method and composition

G - Physics – 01 – N

Patent

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167/163, 167/43

G01N 33/53 (2006.01) A61K 9/10 (2006.01) G01N 33/564 (2006.01)

Patent

CA 1201382

ABSTRACT OF THE DISCLOSURE An assay for detecting SLE antibodies utilizing a novel liposome composition in which there is entrapped a divalent cation responsive indicator. The presence of such antibodies is detected by their stabilization of the supermolecular structure of the liposomes. Such stalization can be detected, and in certain cases, caused by, the addition of magnesium or calcium ions.

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