Luteinizing hormone releasing hormone antagonist peptides

Details Luteinizing hormone releasing hormone antagonist peptides Luteinizing hormone releasing hormone antagonist peptides

C - Chemistry, Metallurgy

07

K

C07K 7/23 (2006.01) A61K 38/09 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2108977

A luteinizing hormone releasing hormone antagonist peptide is provided which effectively decreases plasma levels of es- trogens and androgens. The peptide exhibits increased levels of potency while at the same time minimizing histamine releasing properties, vascular permeability (or edematogenic effects), hypotension, poor water solubility an inadequate duration of action associated with luteinizing hormone releasing hormone antagonist peptides of the past.

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