Lxr ligand binding domain (lxr lbd) crystals

Details Lxr ligand binding domain (lxr lbd) crystals Lxr ligand binding domain (lxr lbd) crystals

C - Chemistry, Metallurgy

07

K

C07K 14/705 (2006.01) G06F 17/50 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2716877

The present invention relates to co-crystals of Liver X receptor beta ligand binding domain (LXR.beta.-LBD) with agonists and to the three-dimensional X-ray crystal structures derived thereof.

La présente invention porte sur des co-cristaux de domaine de liaison au ligand du récepteur du foie X-bêta (LXRß-LBD) avec des agonistes et sur les structures cristallines par rayons X tridimensionnelles issues de ceux-ci.

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