Ly6h gene

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/11 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 15/63 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2342770

The invention provides a brain-specific gene useful in treating Alzheimer's disease, for instance, which comprises a nucleotide sequence cording for the amino acid sequence shown in SQ ID N0:1 and fragments thereof; an expression vector comprising the gene; a host cell comprising the expression vector; an expression product of the gene; an antibody against the product; a therapeutic and prophylactic composition for neurodegenerative disease; and the like.

L'invention porte sur un gène spécifique du cerveau et utilisé dans le traitement de la maladie d'Alzheimer, entre autre. Ce gène renferme une séquence de base codant la séquence d'acides aminés représentée par le NO ID SEQ: 1. Cette invention porte également sur un fragment de cette séquence, sur un vecteur d'expression contenant le gène; sur une cellule d'hôte contenant le vecteur d'expression; sur un produit d'expression du gène; sur un anticorps contre celui-ci et sur des remèdes et agents préventifs des maladies de dégénérescence des nerfs, etc.

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