C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 39/02 (2006.01) C07K 14/20 (2006.01) C07K 16/12 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2294568
The present invention relates to novel vaccines for the prevention or attenuation of Lyme disease. The invention further relates to isolated nucleic acid molecules encoding antigenic polypeptides of Borrelia burgdorferi. Antigenic polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. The invention additionally relates to diagnostic methods for detecting Borrelia gene expression.
Cette invention se rapporte à de nouveaux vaccins permettant de prévenir ou d'atténuer la maladie de Lyme. Cette invention se rapporte en outre à des molécules d'acides nucléiques isolées codant des polypeptides antigéniques de Borrelia burgdorferi. Cette invention présente également des polypeptides antigéniques, ainsi que des vecteurs, de cellules hôtes et des procédés de recombinaison pour la production de ceux-ci. Cette invention se rapporte en outre à des procédés de diagnostic pour détecter l'expression de gènes de Borrelia.
Choi Gil H.
Erwin Alice L.
Hanson Mark S.
Lathigra Raju
Gowling Lafleur Henderson Llp
Human Genome Sciences Inc.
Medimmune Inc.
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