Lymphatic and blood endothelial cell genes

Details Lymphatic and blood endothelial cell genes Lymphatic and blood endothelial cell genes

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 35/14 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2478063

The invention provides polynucleotides and genes that are differentially expressed in lymphatic versus blood vascular endothelial cells. These genes are useful for treating diseases involving lymphatic vessels, such as lymphedema, various inflammatory diseases, and cancer metastasis via the lymphatic system.

L'invention concerne des polynucléotides et des gènes qui sont exprimés différemment dans les cellules endothéliales vasculaires sanguines et lymphatiques. Ces gènes sont des cibles utiles pour le traitement de maladies impliquant les vaisseaux lymphatiques, telles que le lymphoedème, diverses maladies inflammatoires et les métastase cancéreuses, par l'intermédiaire du système lymphatique.

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