Lymphotoxin beta receptor agents in combination with...

Details Lymphotoxin beta receptor agents in combination with... Lymphotoxin beta receptor agents in combination with...

A - Human Necessities

61

K

A61K 39/395 (2006.01)

Patent

CA 2509495

This invention features combination therapies that include a composition that activates lymphotoxin-beta receptor signaling in combination with one or more other chemotherapeutic agents, as well as therapeutic methods and screening methods for identifying agents that in combination with a lymphotoxin-beta receptor agonist agent have a supra-additive effect on tumor inhibition.

L'invention concerne des thérapies de combinaison comprenant une composition activant la signalisation de récepteur bêta de la lymphotoxine en combinaison avec un ou plusieurs agents chimiothérapeutiques, ainsi que des méthodes thérapeutiques et des méthodes de criblage permettant d'identifier les agents qui présentent, en combinaison avec un agent agoniste des récepteurs bêta de la lymphotoxine, un effet supra-additif sur l'inhibition des tumeurs.

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