F - Mech Eng,Light,Heat,Weapons – 25 – D
Patent
F - Mech Eng,Light,Heat,Weapons
25
D
62/1
F25D 11/00 (2006.01) F25D 31/00 (2006.01)
Patent
CA 1314399
ABSTRACT OF THE DISCLOSURE The invention provides containers useful for freeze- drying of biological and other materials which can be advantageously subjected to a lyophilization process, such materials including proteinaceous materials from which moisture is removed in order to preserve the material in a dry, shelf- stable form. The present containers allow lyophilization of the contained material with a minimum of time and energy expenditure by forming the material into a frozen shell to increase the surface area of the material and to minimize the thickness of a given quantity of material which is to be lyophilized. In a typical embodiment of the invention, a container is provided with a congruent, flexible core which is inserted into the container to force the material into the space lying between the container and the core. Expansion of the material on freezing acts to deform the flexible core rather than to break the container. The material thus frozen into a shell-like conformation within the container is then subjected to a lyophilization process after removal of the flexible core.
600693
Haast William E.
Mccarthy Tetrault Llp
LandOfFree
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